DNA Methylation Pattern in Overweight Women under an Energy-Restricted Diet Supplemented with Fish Oil

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DNA Methylation Pattern in Overweight Women under an Energy-Restricted Diet Supplemented with Fish Oil

Dietary factors modulate gene expression and are able to alter epigenetic signatures in peripheral blood mononuclear cells (PBMC). However, there are limited studies about the effects of omega-3 polyunsaturated fatty acids (n-3 PUFA) on the epigenetic mechanisms that regulate gene expression. This research investigates the effects of n-3-rich fish oil supplementation on DNA methylation profile ...

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Oat beta-glucan supplementation does not enhance the effectiveness of an energy-restricted diet in overweight women.

Epidemiological evidence shows an inverse relationship between dietary fibre intake and body weight gain. Oat beta-glucan, a soluble fibre alters appetite hormones and subjective satiety in acute meal test studies, but its effects have not been demonstrated with chronic consumption. The present study aimed to test the effects in women of two different doses of oat beta-glucan on weight loss and...

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Meat quality of rabbits fed a diet supplemented with fish oil and antioxidant*

The aim of the study was to determine the relative percentage of individual fatty acids and cholesterol content in the muscles of the rabbit hind leg as well as to estimate the efficiency of transfer of fatty acids from feed to tissue as affected by supplementation the diet with fish oil and vitamin E. Three groups of New Zealand White rabbits were used (one control and two experimental) with 4...

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Methylation pattern of fish lymphocystis disease virus DNA.

The content and distribution of 5-methylcytosine in DNA from fish lymphocystis disease virus was analyzed by high-pressure liquid chromatography, nearest-neighbor analysis, and with restriction endonucleases. We found that 22% of all C residues were methylated, including methylation of the following dinucleotide sequences: CpG to 75%, CpC to ca. 1%, and CpA to 2 to 5%. Comparison of relative di...

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effect of energy-restricted diet in combination with calcium supplement or low-fat milk on iron status of overweight or obese premenopausal women

background: although it is assumed that calcium has beneficial effects on weight loss, the interaction of calcium and iron would be a major concern. we did this study to investigate the effects of calcium and low-fat milk on serum ferritin in overweight or obese premenopausal women.   methods: sixty-four healthy overweight or obese premenopausal women recruited in shahid beheshti university of ...

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ژورنال

عنوان ژورنال: BioMed Research International

سال: 2014

ISSN: 2314-6133,2314-6141

DOI: 10.1155/2014/675021